SBDS Antikörper (AA 1-250)

Produktnummer ABIN5775988

Der Maus Monoklonal Anti-SBDS Antikörper wurde für WB, ELISA, IF und ICC validiert. Er ist geeignet, SBDS in Proben von Human zu detektieren.

Kurzübersicht für SBDS Antikörper (AA 1-250) (ABIN5775988)

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SBDS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AT1E8

Produktdetails anti-SBDS Antikörper

Bindungsspezifität: AA 1-250

Verwendungszweck: Human SBDS antibody

Aufreinigung: Purified

Immunogen: Recombinant human SBDS (1-250aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Andere Bezeichnung: SBDS

Hintergrund: The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.

NCBI Accession: NP_057122

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly